Bioinformatics Core

The Bioinformatics Core offers a wide range of bioinformatics services for researchers at the UKE and related institutions. The main focus is on the analysis of high-throughput sequencing data. Services offered include data analysis, consulting, software development, and training.

Services

  • For many data analysis tasks standardized workflows, following published best-practices, are established at the Bioinformatics Core. For solving tasks were these workflows do not suffice, customized and integrative solutions are provided. In both cases the facility operates with a high degree of transparency, explaining and documenting analysis strategies and assessing results jointly with clients.

    Examples of applications for which bioinformatical solutions are provided:

    • RNA-Seq (differential and absolute expression, fusion genes, small RNAs)
    • Genotyping
    • ChIP-Seq
    • Metagenomics and Metatranscriptomics
    • Assemblies
    • Gene Prediction
    • Ribo-Seq
    • MeDIP-Seq
    • Bisulfite Sequencing
    • and many other applications

  • The facility provides bioinformatical consulting on various aspects of sequencing and sequence data analysis. Many research projects are supported over their whole live cycle. This includes initial project planning, official support for grant applications and documentation of bioinformatical methods for publications.
    Additionally the Bioinformatics Core gives advice on hardware and software solutions for workgroups who plan to carry out some or all analyzes by themselves.

  • The Bioinformatics Core has substantial expertise in developing custom software and workflows for sequence data analysis. Software development, however, is a time consuming process and thus the facility is forced to carefully evaluate the feasibility of proposed projects.

  • Regularly two workshops are held: “Applied Bioinformatics”, focuses on bioinformatics techniques for laboratory use and “An Introduction to Scientific Programming” aims to teach basic programming skills to attendees without substantial programming experience. The Bioinformatics Core is open for suggestions on other bioinformatical topics.

Contact

Malik Alawi
Dr.
Malik Alawi
M. Sc.
  • Core manager
Location

W36 , Ground Floor, Room number 10
Ann-Kristin Afflerbach
Dr. rer. biol. hum.
Ann-Kristin Afflerbach
  • Research fellow
Location

Campus Forschung I - N27 , 4th Floor, Room number 04.023
Ceren Saygi
Dr.
Ceren Saygi
  • Bioinformatics Facility
Location

W36 , Ground Floor, Room number 07
Christian Müller
Christian Müller
M. Sc.
  • Bioinformatics Facility
Location

W36 , Ground Floor, Room number 12
Christian Casar
Christian Casar
M. Sc.
  • Bioinformatics Facility
Location

W36 , Ground Floor, Room number 08
Michael Spohn
Michael Spohn
M. Sc.
  • Bioinformatics Facility
Location

W36 , Ground Floor, Room number 09
Dr.
Philipp Dirksen
  • Bioinformatics Facility
Location

W36 , Ground Floor, Room number 12

References / Publications

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